Quinine for muscle cramps

Quinine for Leg Cramps.

Practice Pointers Muscle cramps affect between 50% and 60% of adults.1 Little is known about their pathophysiology, so many remedies are used empirically. A crystalline alkaloid powder extracted from the bark of the South American cinchona tree, quinine is well known for its use in treating malaria and providing the bitter flavor for tonic water. Quinine has been used by the Quechua of South Am...

Quinine for night cramps.

counselling. Fellow workers as well as employers should be well informed and concerned. A protective code of practice was thought desirable; but the Manpower Services Commission produced a good one on disability in general last year, and that is not well enough known.7 It is highly relevant to epilepsy both on recruitment and on promoting the interests of existing employees. In the spirit of th...

Muscle cramps.

Muscle cramps are a common problem characterized by a sudden, painful, involuntary contraction of muscle. These true cramps, which originate from peripheral nerves, may be distinguished from other muscle pain or spasm. Medical history, physical examination, and a limited laboratory screen help to determine the various causes of muscle cramps. Despite the "benign" nature of cramps, many patients...

Quinine: not a safe drug for treating nocturnal leg cramps.

N-of-1 trials of quinine efficacy in skeletal muscle cramps of the leg.

BACKGROUND Skeletal muscle cramps affect over a third of the ambulatory elderly population. Quinine is the established treatment, but there are safety concerns, and evidence for efficacy is conflicting. A recent meta-analysis established a small advantage for quinine, but identified the need for additional studies. N-of-1 trials compare two treatments, in a randomised, double-blind, multiple cr...